Research Studies
The mythical pomegranate has been a scientific enigma since biblical times. Recent interest in the therapeutic properties of the pomegranate has resulted in a number of independent clinical studies from scientists around the world that have begun to substantiate the pomegranate's legendary powers.
We have included links to some of these independently published studies.
- Chemopreventive and Adjuvant Therapeutic Potential of Pomegranate (Punica granatum) for Human Breast Cancer Nam Deuk Kim, Rajendra Mehta, Weiping Yu, Ishak Neeman, Talia Livney, Akiva Amichay, Donald Poirier, Paul Nicholls, Andrew Kirby, Wenguo Jiang, Robert Mansel, Cheppail Ramachandran, Thangaiyan Rabi, Boris Kaplan and Ephraim Lansky. Breast Cancer Research and Treatment, 71: 203-217, 2002.
- Pomegranate Extracts Potently Suppress Proliferation, Xenograft Growth, and Invasion of Human Prostate Cancer Cells Martin Albrecht, Wenguo Jiang, James Kumi-Diaka, Ephraim P. Lansky, Lyndon M. Gommersall, Amit Patel, Robert E. Mansel, Ishak Neeman, Albert A. Geldof, Moray J. Campbell. Journal of Medicinal Food. 2004, 7(3): 274-283.
- Pomegranate (Punica granatum) Pure Chemicals Show Possible Synergistic Inhibition of Human PC-3 Prostate Cancer Cell Invasion Across Matrigel Ephraim Philip Lansky, Gregory Harrison, Paul Froom and Wen G. Jiang. Investigational New Drugs 23: 121-122, 2005.
- Possible Synergistic Prostate Cancer Suppression by Anatomically Discrete Pomegranate Fractions Ephraim P. Lansky, Wenguo Jiang, Huanbiao Mo, Lou Bravo, Paul Froom, Weiping Yu, Neil M. Harris, Ishak Neeman and Moray J. Campbell. Investigational New Drugs 23: 11-20, 2005.
- Chemopreventive Effects of Pomegranate Seed Oil on Skin Tumor Development in CD Mice Justin J. Hora, Emily R. Maydew, Ephraim P. Lansky, and Chandradhar Dwivedi. Journal of Medicinal Food, 6 (3) 2003, 157-161.
- Pomegranate as a Cosmeceutical Source: Pomegranate Fractions Promote Proliferation and Procollagen Synthesis and Inhibit Matrix Metalloproteinase-1 Production in Human Skin Cells Aslam MN, Lansky EP, Varani J. J Ethnopharmacol. 2006 Feb 20; 103(3): 311-8.
- Dietary Effect of a Pomegranate Seed Oil Rich in 9cis, 11trans, 13cis Conjugated Linolenic Acid on Lipid Metabolism in Obese, Hyperlipidemic OLETF Rats Keisuke Arao, Yu-Ming Wang, Nao Inoue, Junichi Hirata, Jae-Young Cha, Koji Nagao and Teruyoshi Yanagita. Lipids in Health and Disease 2004, 3: 24.
- Rapid Dereplication of Estrogenic Compounds in Pomegranate (Punica granatum) Using On-Line Biochemical Detection Coupled to Mass Spectrometry Danny A. van Elswijk, Uwe P. Schobel, Ephraim Lansky, Hubertus Irth, Jan van der Greef. Phytochemistry 65 (2004) 233-241.
- Preliminary Studies on the Anti-Angiogenic Potential of Pomegranate Fractions in Vitro and in Vivo Masakazu Toi, Hiroko Bando, Cheppail Ramachandran, Steven J. Melnick, Atsushi Imai, Rose S. Fife, Raymond Eric Carr, Tsutomu Oikawa & Ephraim Philip Lansky. Angiogenesis 6: 121-128, 2003.
- Antioxidant and Eicosanoid Enzyme Inhibition Properties of Pomegranate Seed Oil and Fermented Juice Flavanoids Shay Yehoshua Schubert, Ephraim Philip Lansky, Ishak Neeman. Journal of Ethnopharmacology 66 (1999) 11-17.